Results
053.65.001 Precise Control of Selectivity in Multi-Route Enzyme Systems
1. W.H. Heijnis, P.A. Wierenga, A.E.M. Janssen, W.J.H van Berkel, H. Gruppen, In-line quantification of peroxidase-catalyzed cross-linking of alpha-lactalbumin in a microreactor, Chemical Engineering Journal (2010), 157, 1, 189-193
2. W.H. Heijnis, P.A. Wierenga, W.J.H. van Berkel, H. Gruppen, Directing the Oligomer Size Distribution of Peroxidase-Mediated Cross-Linked Bovine alpha-Lactalbumin, Journal of Agricultural and Food Chemistry (2010), 58, 9, 5692-5697
3. W.H. Heijnis, H.L. Dekker, L.J. de Koning, P.A. Wierenga, A.H. Westphal, C.G. de Koster, H. Gruppen, W.J.H. van Berkel, Identification of the Peroxidase-Generated Intermolecular Dityrosine Cross-Link in Bovine alpha-Lactalbumin, Journal of Agricultural and Food Chemistry (2011), 59, 1, 444-449
053.65.002 Enzyme-Based Nanoscale Multistep Reactors
1. J.A. Opsteen, R.P. Brinkhuis, R.L.M. Teeuwen, D.W.P.M. Löwik, J.C.M. van Hest, "Clickable" polymersomes, Chemical Communications (2007), 30, 3136-3138
2. M. Yang, R.L.M. Teeuwen, M. Giesbers, J. Baggerman, A. Arafat, F.A. de Wolf, J.C.M. van Hest, H. Zuilhof, One-step photochemical attachment of NHS-terminated monolayers onto silicon surfaces and subsequent functionalization, Langmuir (2008), 24, 15, 7931-7938
3. M.W.T. Werten, A.P.H.A. Moers, T. Vong, H. Zuilhof, J.C.M. van Hest, F.A. de Wolff,Biosynthesis of an amphiphilic silk-like polymer, Biomacromolecules (2008), 9, 7, 1705-1711
4. S.F.M. van Dongen, R.l.M. Teeuwen, M. Nallani, S.S. van Berkel, J.J.L.M. Cornelissen, R.J.M. Nolte, J.C.M. van Hest, Single-Step Azide Introduction in Proteins via an Aqueous Diazo Transfer, Bioconjugate Chemistry (2009), 20, 1, 20-23
5. R.L.M. Teeuwen, H. Zuilhof, F.A. de Wolf, and J.C.M. van Hest, Temperature-controlled positioning of fusion proteins in microreactors, Soft Matter (2009), 5, 2261 –2268
6. R.L.M. Teeuwen, S.S. van Berkel, T.H.H. van Dulmen, S. Schoffelen, S.A. Meeuwissen, H. Zuilhof, F.A. de Wolf, J.C.M. van Hest, “Clickable” elastins: elastin-like polypeptides functionalized with azide or alkyne groups, Chemical Communications (2009), 27, 4022–4024
7. R. Schipperus, R.L.M. Teeuwen, M.W.T. Werten, G. Eggink, F.A. de Wolf, Secreted production of elastin-like polypeptides by Pichia pastoris, Applied Microbiology and Biotechnology (2009), 85, 2, 293
8. R.L.M. Teeuwen, F.A. de Wolf, H. Zuilhof, and J.C.M. van Hest, Elastin-like polypeptides of different molecular weight show independent transition temperatures when mixed, Soft matter (2009), 5, 21, 4305
9. T. Vong, J. ter Maat, T.A. van Beek, B. van Lagen, M. Giesbers, J.C. M. van Hest, H. Zuilhof, Site-Specific Immobilization of DNA in Glass Microchannels via Photolithography, Langmuir, (2009), 25, 24, 13952
053.65.003 Versatile Micro-NMR
1. P.J.M. van Bentum, J.W.G. Janssen, A.P.M. Kentgens, J. Bart, J.G.E. Gardeniers, Stripline probes for nuclear magnetic resonance, Journal of Magnetic Resonance (2007), 189, 1, 104-113
2. A.P.M. Kentgens, J. Bart, P.J.M. van Bentum, A. Brinkmann, E.R.H. van Eck, J.G.E. Gardeniers, J.W.G. Janssen, P. Knijn, S. Vasa and M.H.W. Verkuijlen, High-resolution liquid- and solid-state nuclear magnetic resonance of nanoliter sample volumes using microcoil detectors, The Journal of Chemical Physics (2008), 128, 5, 052202
3. J. Bart, A.J. Kolkman, A.J. Oosthoek-de Vries, K. Koch, P.J. Nieuwland, H.J.W.G. Janssen, J.P.J.M. van Bentum, K.A.M. Ampt, F.P.J.T. Rutjes, S.S. Wijmenga, H.J.G.E. Gardeniers, A.P.M. Kentgens, A Microfluidic High-Resolution NMR Flow Probe, Journal of the American Chemical Society (2009), 131, 14, 5014
4. J. Bart, J.W.G. Janssen, P.J.M. van Bentum, A.P.M. Kentgens, J.G.E. Gardeniers, Optimization of stripline-based microfluidic chips for high-resolution NMR, Journal of Magnetic Resonance (2009), 201, 175
5. J. Bart, R.M. Tiggelaar, M. Yang, S. Schlautmann, H. Zuilhof, J.G.E. Gardeniers, Roomtemperature intermediate layer bonding for microfluidic devices, Lab Chip (2009) 9, 3481
6. J. Bart and J.G.E. Gardeniers, ‘On-line monitoring of reaction kinetics inmicroreactors using MS and micro NMR’ Micro Process Engineering: A Comprehensive Handbook, Volume 3, V. Hessel, J.C. Schouten (eds.), Wiley-VCH, 135 (2009).
053.65.004 CCS Chipchemstation
1. W.P. Bula, W. Verboom, D.N. Reinhoudt, J.G.E. Gardeniers, Multichannel quench-flow microreactor chip for parallel reaction moni, Lab on a Chip (2007), 7, 12, 1717-1722
2. M.J.W. Ludden, X.Y. Ling, T. Gang, W.P. Bula, H.L.G.E. Gardeniers, D.N. Reinhoudt, J. Huskens, Molecular printboards inside microfluidic devices: small molecule and antibody recognition, Chemistry - A European Journal (2008), 14, 1, 136
053.65.005 Massive Parallelisation of Multi-Chamber Reaction and Separation Microreactors
1. J. de Jong, B. Ankoné, R.G.H. Lammertink, M. Wessling, New replication technique for the fabrication of thin polymeric microfluidic devices with tunable porosity, Lab on a Chip (2005), 5, 11, 1240-1247
2. J. de Jong, R.G.H. Lammertink, M.Wessling, Membranes and microfluidics: a review, Lab on a Chip (2006), 6, 9, 1125-1139
3. J. de Jong, M.J. Geerken, R.G.H. Lammertink, M. Wessling, Porous microfluidic devices - Fabrication and applications, Chemical Engineering & Technology (2007), 30, 3, 309-315
4. J. de Jong, P.W. Verheijden, R.G.H. Lammertink, M. Wessling M, Generation of local concentration gradients by gas-liquid contacting, Analytical Chemistry (2008), 80, 9, 3190-3197
5. J.W. Swarts, R.C. Kolfschoten, M.C.A.A. Jansen, A.E.M. Janssen, R.M. Boom, Effect of diffusion on enzyme activity in a microreactor, Chemical Engineering Journal (2010), 162, 1, 301-306
6. R.C. Kolfschoten, A.E.M. Janssen, R.M. Boom, High-throughput separation in a microfluidic device with multiple contacting regions, New Biotechnology (2009), 25, S164-S164
053.65.006 Multi-Phase Microreactors as basis for Process Intensification
1. T.J.A. Renckens, A.R. Almeida, M.R. Damen, M.T. Kreutzer, G. Mul, Product desorption limitations in selective photocatalytic oxidation, Catalysis Today (2010), 155, 3-4, 302-310